α-Cyclodextrins Polyrotaxane Loading Silver Sulfadiazine
نویسندگان
چکیده
منابع مشابه
Properties of silver sulfadiazine-resistant Enterobacter cloacae.
Two silver sulfadiazine-resistant isolates of Enterobacter cloacae obtained in a burns unit where the drug was in use were studied. These strains were resistant to elevated levels of the drug, and they were cross-resistant to silver benzoate, but not to silver nitrate. Growth of the strains in nutritionally poor defined media sensitized them to the inhibitory action of the drug. Exposure of the...
متن کاملSolubility of silver sulfadiazine in physiological media and relevance to treatment of thermal burns with silver sulfadiazine cream.
Silver sulfadiazine cream has been a standard treatment for burns over the past two decades. Although many studies have described the phenomenon of silver absorption from burn wounds treated with silver sulfadiazine, they failed to examine the chemistry underlying the absorption process: Silver chloride was assumed to form at the burn wound and absorption of silver was believed to be negligible...
متن کاملSilver sulfadiazine: effect on the growth and metabolism of bacteria.
Even though the addition of silver sulfadiazine (AgSu) to purified deoxyribonucleic acid (DNA) results in the formation of AgSu-DNA complexes, no such complexes were detected in bacteria treated with AgSu. AgSu blocked macromolecular syntheses in treated bacteria, DNA synthesis being slightly more sensitive to this inhibitory action. The ribosomes, ribonucleic acid, and DNA isolated from treate...
متن کاملMechanism of silver sulfadiazine action on burn wound infections.
The role of silver and sulfadiazine in the mechanism of action of silver sulfadiazine on burn wound infections was investigated. Silver, but not sulfadiazine, was bound by bacteria. Sulfadiazine did not act as an antibacterial agent in low concentrations, but exhibited specific synergism in combination with subinhibitory levels of silver sulfadiazine. The efficacy of silver sulfadiazine is thou...
متن کاملExperimental burns: Comparison between silver sulfadiazine and photobiomodulation.
OBJECTIVE To analyze morphological characteristics and organization of the collagen fibers of third degree burns from scalding compared to laser therapy and silver sulfadiazine, the latter considered as the gold standard. METHOD Were selected 12 animals (Rattus norvegicus) also divided into three groups (control group [CG] - untreated burns; sulfadiazine group [SG] - burns were treated with s...
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ژورنال
عنوان ژورنال: Polymers
سال: 2018
ISSN: 2073-4360
DOI: 10.3390/polym10020190